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In this review, we aim to summarize our current understanding of eryptosis, formulate a nomenclature and guidelines to interpret results of eryptosis studies, provide a synopsis of morphological and biochemical features of eryptosis, and highlight the role of eryptosis in health and disease, including its druggability

The absence of functional CFTR disrupts epithelial water and ion homeostasis, leading to the accumulation of dehydrated mucus, recurrent bacterial infections, and ultimately organ failure and other life-threatening consequences [78]

Vogel JU, Cinatl J, Dauletbaev N, et al

Digenic mutations in ALDH2 and ADH5 impair formaldehyde clearance and cause a multisystem disorder, AMeD syndrome